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epigenetics

noun

/ˌɛp ɪ dʒəˈnɛt ɪks/

IPA:

Dictionary definition of epigenetics

The study of heritable changes in gene expression that occur without alterations to the underlying DNA sequence.
"Epigenetics explores how environmental factors can influence gene expression."

Detailed meaning of epigenetics

It investigates how external factors and environmental influences can modify gene activity and gene function, leading to phenotypic variations. Epigenetic mechanisms involve chemical modifications, such as DNA methylation or histone modifications, that can affect gene expression by turning genes "on" or "off" or modulating their activity levels. These modifications can be influenced by a variety of factors, including lifestyle choices, environmental exposures, stress, nutrition, and even social interactions. Epigenetics plays a crucial role in developmental processes, cell differentiation, and disease development. It provides insights into how gene-environment interactions shape an individual's health and disease susceptibility, offering a more nuanced understanding of genetic inheritance beyond the DNA sequence itself. Epigenetics has the potential to contribute to fields like medicine, agriculture, and environmental sciences by providing a framework for understanding the complex interplay between genes and the environment.

Example sentences containing epigenetics

1. Epigenetics explores the heritable changes in gene expression without altering the DNA sequence.
2. Recent research in epigenetics has shed light on the role of environmental factors in gene regulation.
3. The study of epigenetics has revolutionized our understanding of how nature and nurture interact.
4. Epigenetics investigates the molecular mechanisms that control gene activity and expression.
5. The field of epigenetics holds promise for personalized medicine and targeted therapies.
6. Epigenetics provides insights into how certain diseases are influenced by genetic and environmental factors.

History and etymology of epigenetics

The term 'epigenetics' has its roots in Greek. It combines two Greek words: 'epi,' which means 'over' or 'above,' and 'genetics,' derived from 'genos,' meaning 'origin' or 'birth.' When combined, 'epigenetics' essentially signifies 'above genetics' or 'beyond genetics.' This etymology reflects the concept that epigenetics pertains to changes in gene expression that occur above or beyond the genetic code itself, encompassing modifications that can be heritable but do not involve alterations to the underlying DNA sequence.

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Further usage examples of epigenetics

1. Scientists are unraveling the epigenetic modifications associated with aging and age-related diseases.
2. The discovery of DNA methylation as an epigenetic mark was a major breakthrough in the field.
3. Epigenetics has implications for understanding the impact of early-life experiences on long-term health outcomes.
4. The study of epigenetics has revealed the potential for transgenerational inheritance of epigenetic marks.
5. Epigenetics highlights the dynamic nature of gene expression and its response to environmental cues.
6. Researchers are exploring the role of epigenetics in cancer development and progression.
7. Epigenetic modifications can be influenced by diet, stress, and other lifestyle factors.
8. Epigenetics has sparked new avenues of research into the prevention and treatment of neurological disorders.
9. The field of epigenetics challenges the notion of genes as fixed and unchangeable entities.
10. The study of epigenetics has led to the development of epigenetic therapies targeting specific diseases.
11. Epigenetic changes can be inherited and passed down from one generation to the next.
12. The epigenome, consisting of various epigenetic marks, regulates gene expression patterns.
13. Epigenetics plays a crucial role in embryonic development and cellular differentiation.
14. Understanding epigenetics may pave the way for interventions that can reverse or mitigate epigenetic alterations associated with diseases.
15. The study of epigenetics has revolutionized our understanding of inherited traits.
16. Researchers are investigating the role of epigenetics in the development of cancer.
17. Epigenetics offers insights into the impact of diet and lifestyle on gene activity.
18. The field of epigenetics aims to unravel the complexities of gene regulation.
19. Epigenetics suggests that our experiences can leave molecular marks on our DNA.
20. Scientists are studying epigenetics to uncover mechanisms of aging and longevity.
21. Epigenetics provides a framework for understanding the interplay between genes and the environment.
22. The emerging field of epigenetics holds promise for personalized medicine.
23. Epigenetics highlights the importance of early-life experiences in shaping health outcomes.
24. The epigenetics of plants can be influenced by environmental cues.
25. Researchers are exploring epigenetics as a potential avenue for therapeutic interventions.