abashed, abject, abscess, beleaguer, besiege, brutality, chide, claustrophobia, compunction, consternation, dank, defamatory, demented, diatribe, disconsolate, dishearten, dismal, dismay, dismayed, distress, dolor, downcast, dreadful, dysphoria, emaciated, frigid, grief, grudge, heartache, heartbreak, hysteria, insufferable, jibe, lovelorn, lugubrious, malady, melancholy, monstrosity, neurosis, objurgate, opprobrious, overemotional, palpitation, perturbed, plaintive, precarious, privation, repugnance, rueful, ruffled, schizophrenia, siege, snide, squalid, suffering, surrender, throe, timorous, torture, trepidation, unapproachable, unfriendly, unsightly, vicious, woebegone, woeful